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GLP-1 research · explained

research · explained

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GLP-1 is a gut hormone involved in glucose-dependent insulin secretion and other metabolic signals. Research on its active form and receptors helped enable medicines that mimic its action. The hormone, a drug and an individual treatment decision are different subjects.

Evidence

Citation Laureates identifies influential research. Recognition is not a prediction of a Nobel winner in a particular year.

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work and contributions

Daniel J. Drucker

An endocrinology researcher whose work clarified the biological actions of GLP-1 and related gut hormones. His research helped connect basic hormone biology with medicines for metabolic disease.

work and contributions

Jens Juul Holst

A physiologist who studies how intestinal hormones regulate insulin secretion and metabolism. His experiments helped establish the activity of GLP-1 and its role in the gut–pancreas connection.

work and contributions

Svetlana Mojsov

A peptide chemist whose work identified the biologically active form of GLP-1 and enabled its synthesis and measurement. This contribution helped researchers test how the hormone stimulates insulin secretion.

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